Hypoglycemia, Diabetes, and Cardiovascular Events

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Hypoglycemia, Diabetes, and Cardiovascular Events

D iabetes is at epidemic proportions in the U.S. Patients with diabetes are at increased risk for microand macrovascular complications. The benefit of glycemic control in decreasing the risk for microvascular disease is well established. However, the role of glycemic control in decreasing macrovascular complications has been controversial. Several large clinical trials looking at this issue hav...

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Association of Clinical Symptomatic Hypoglycemia With Cardiovascular Events and Total Mortality in Type 2 Diabetes

OBJECTIVE Hypoglycemia is associated with serious health outcomes for patients treated for diabetes. However, the outcome of outpatients with type 2 diabetes who have experienced hypoglycemia episodes is largely unknown. RESEARCH DESIGN AND METHODS The study population, derived from the National Health Insurance Research Database released by the Taiwan National Health Research Institutes duri...

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Cardiovascular Implications of Hypoglycemia in Diabetes Mellitus.

C ase presentation: An 81-year-old man presents to the physician's office for a routine review. He has had a previous myocardial infarction treated with percutaneous coronary intervention , and has a history of hypertension, dyslipidemia, and type 2 diabetes mel-litus complicated by stage 3a chronic kidney disease. Medical therapy includes aspirin, clopidogrel, metfor-min 1000 mg twice daily, a...

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Diabetes and Cardiovascular Disease Serious Cardiovascular Outcomes in Diabetes The Role of Hypoglycemia

Hypoglycemia is a well-recognized side effect of glucoselowering therapies in patients with diabetes mellitus. The incidence of mild self-reported hypoglycemic episodes in patients with type 1 diabetes mellitus is approximately 30 episodes per patient per year, whereas the incidence of severe hypoglycemic episodes (ie, those that require third-party assistance) may be as high as 3.2 episodes pe...

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Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes

OBJECTIVE Frequent episodes of severe hypoglycemia may increase the risk of cardiovascular disease (CVD) in people with diabetes. Our aim was to study the relationship between severe hypoglycemic episodes and CVD incidence in subjects with type 1 diabetes, and further, to assess if markers of inflammation/endothelial injury were enhanced in individuals who experienced hypoglycemic episodes. R...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2010

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc09-2082